bringing novel prescription medicines
to the global market for essential supportive care for
people undergoing treatment for diseases such as cancer
Our mission is to develop and commercialize medicines that support the comfort, quality of life, and dignity of people with treatment-related GI distress, specifically overactive bowel, which includes symptoms of chronic diarrhea, urgency, and incontinence.
Our paramount near-term clinical activity is our Phase 3 pivotal OnTarget trial of Mytesi® (crofelemer) for the follow-on indication of the preventative treatment of chemotherapy-induced overactive bowel (CIOB). We have completed patient enrollment for OnTarget – a key step on our journey to making crofelemer available to treat the neglected comorbidity of CIOB – and top line results from this pivotal study are expected in late October 2023.
Our medicines are responsibly harvested from plants located in rainforest regions.
Our medicines work by a novel mechanism of action: the inhibitory modulation of two secretory chloride ion channels in the gastrointestinal tract.